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MAO inhibitors

Monoamine Oxidase Inhibitors for Neurological Disorders: A review

Ram Singh, Geetanjali ., Naveen Sharma

Abstract


Neurological disorders are drawing much attention from scientists in recent times. These disorders are one of the most serious disorders mankind will have to fight against in the very near future. Monoamine oxidase is one target which is responsible for many neurological disorders. Scientists have studied different molecular entities as monoamine oxidase inhibitors. The MAO-A and -B inhibitors have been developed to increase the available amounts of monoamine neurotransmitters in the brains for the treatment of neurological disorders. In this article, selected classes of compounds like coumarins, chromones, isatins, phthalimides, phthalonitriles and quinolinones have been shown as potential inhibitors of human MAO-A and MAO-B.


Keywords


Chromone; Coumarin; Isatin; Phthalonitrile; Quinolinone; MAO-A; MAO-B; FAD; Neurological disorders

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References


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