Buta-1,3-diynes synthesis

Unprecedented Palladium catalyzed Homo-Coupling Reaction of terminal E-diiodoalkanes towards the synthesis of Buta-1,3-diynes

Sudhir K. Sharma


An efficient method for the synthesis of Buta-1,3-diynes have been doveloped via homocoupling reaction of terminal (E)-1,2-diiodoalkene under Suzuki reaction condition. The method has been successfully applied both on aliphatic and aromatic E-diiodoalkene resulting buta-1,3-diynes prepared in good yields.


Cycloaddition; Cross-coupling; Cyclocondensation; Alkynes; Homocoupling

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ISSN 2348 – 1889