herbal nanomedicine review

Herbal nanomedicine interactions to enhance pharmacokinetics, pharmaco-dynamics, and therapeutic index for better bioavailability and biocompatibility of herbal formulations

Raiv Kumar, Munesh Sharma

Abstract


The recent technological advancement in nanotechnology has unlocked new avenues for research and development in the field of phyto-medicine. Development of reliable and eco-friendly synthesis of nanoparticles is a significant advancement for starter nanotechnology to develop noble nanomedical delivery system of herbs (HNMDS), and have to overcome the downsides of old-style herbs-medicines delivery means through analyzing the interactions between nanocarriers and herbs or phyto-medicine. The application of nanotechnological ways and means for bioavailability and biocompatibility enrichment of phyto-medicine must be reread and need swift efforts to develop new formulations. Nanotechnology empowers the combination of hitherto separate approaches to health care by letting the realization of so-called ’theranostic’ applications, as well as besieged blend products. Formulation must also release active ingredient from phyto-formulation as emerging nano dosage forms having number of benefits existed earlier in phyto-medicine. This assessment converses nano sized herbal nanomedicines delivery carries, potential current and ultramodern advances for enhancing the activity and overcoming problems associated with herbal medicines for the development of novel HNMDS. Clinical Pharmacokinetics is discussed in view of the impression of advance of drug absorption, distribution, metabolism, and excretion as per the entitlement of pharmacokinetic principles of the harmless and actual therapeutic applications of herbal nanomedical medications.

Keywords


Phyto-medicine; Herb-to-nanoparticle interactions; Hydrophilicity; Lipophilicity; Bioavailability; Nanocarriers

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ISSN 2394-0867