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Synthesis and characterization of Dendrimer modified Magnetite nanoparticles and their Antimicrobial activity for Toxicity analysis

Neha Sardana, Kailash Singh, Mukesh Saharan, Deepak Bhatnagar, Rishabh Shrivastava Ronin


Interest has been shown in iron magnetite nanoparticles because of its various important properties such as large surface area with high surface-to-volume ratio, ease of separation, water solubility, super paramagnetism and biocompatibility.  In addition to this, due to large surface area, dendrimers can also be attached easily. In the present study, Fe3O4 magnetic nanoparticles were synthesizedbyco-precipitationmethod and cascading polyamidoaminedendrimersweresynthesized on   the surface of these nanoparticles.Structural analysis of these particles was done by XRD and FTIR. SEM showed clear dispersion of the Dendrimer-modified magnetic nanoparticles. Furthermore, antimicrobial activity of these nanoparticles was studied against microbial strains Escherichia coli and Staphylococcus aureus.


Polyamidoamine (PAMAM) Dendrimer; Magnetite Nanoparticle; Antimicrobial Activity

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